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KMID : 0357920110450060557
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Korean Journal of Pathology
2011 Volume.45 No. 6 p.557 ~ p.563
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Type and lncidence of Soft Tissue Sarcomas in Korea: 2001-2007
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Choi Kyung-Un
Kang Hae-Youn
Koo Hea-Soo
Kwon Mi-Seon
Kim Dong-Hoon
Kim Mi-Jung
Kim Su-Jin
Kim Young-Sil
Kim Chul-Hwan
Park Yong-Koo
Park Hye-Rim
Paik Seung-Sam
Yoo Jin-Young
Lee An-Hi
Lee Jae-Hyuk
Lee Hye-Kyung
Jang Kyu-Yun
Chu Young-Chae
Choi Joon-Hyuk
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Abstract
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Background : The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to provide the clinicopathologic characteristics of STS within the population of the Republic of Korea.
Methods : The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed.
Results : Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent adverse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities.
Conclusions : We reported the distribution and characteristics of STS in the Republic of Korea.
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KEYWORD
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Sarcoma, Korea, Incidence, Type, Prognosis
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